Genes involved in organ separation in Arabidopsis: an analysis of the cup-shaped cotyledon mutant. Temporal control of leaf complexity by miRNA-regulated licensing of protein complexes. Model for the regulation of Arabidopsis thaliana leaf margin development. Coupled enhancer and coding sequence evolution of a homeobox gene shaped leaf diversity. A growth-based framework for leaf shape development and diversity. Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates. Stage-specific regulation of Solanum lycopersicum leaf maturation by class 1 KNOTTED1-LIKE HOMEOBOX proteins. Homologies in leaf form inferred from KNOXI gene expression during development. ASYMMETRIC LEAVES1 and auxin activities converge to repress BREVIPEDICELLUS expression and promote leaf development in Arabidopsis. A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis. The developmental gene Knotted-1 is a member of a maize homeobox gene family. The making of a compound leaf: genetic manipulation of leaf architecture in tomato. Hareven, D., Gutfinger, T., Parnis, A., Eshed, Y. A developmental framework for dissected leaf formation in the Arabidopsis relative Cardamine hirsuta. A conserved molecular framework for compound leaf development. The genetic basis for differences in leaf form between Arabidopsis thaliana and its wild relative Cardamine hirsuta. Leaf shape evolution through duplication, regulatory diversification, and loss of a homeobox gene. Morphogenesis of simple and compound leaves: a critical review. Thus, a conserved developmental mechanism promotes simple leaf architecture in which CIN-TCP–KNOX-II forms a strong differentiation module that suppresses the KNOX-I-CUC network and leaflet initiation.Įfroni, I., Eshed, Y. Simultaneous downregulation of CIN-TCP and KNOX-II in Arabidopsis leads to the reactivation of the stemness genes KNOX-I and CUPSHAPED COTYLEDON ( CUC) and triggers ectopic organogenesis, eventually converting the simple lamina to a super-compound form that appears to initiate leaflets indefinitely. Here, we show that the CINCINNATA-like TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORS (CIN-TCP) transcription factors activate the class II KNOTTED1-LIKE ( KNOX-II) genes and the CIN-TCP and KNOX-II proteins together redundantly suppress leaflet initiation in simple leaves. The mechanistic basis of margin dissection and leaflet initiation has been inferred primarily by analysing compound-leaf architecture, and thus whether the intact lamina of simple leaves has the potential to initiate leaflets upon endogenous gene inactivation remains unclear. Angiosperm leaves show extensive shape diversity and are broadly divided into two forms simple leaves with intact lamina and compound leaves with lamina dissected into leaflets.

Leaf primordia